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Molecular Biology News
September 28, 2020

Top Headlines
 

Mystery of Giant Proton Pump Solved

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a ...

Customizable Synthetic Antibiotic Outmaneuvers Resistant Bacteria

Antibiotic resistance is one of the world's most urgent public health threats. In the United States alone, tens of thousands of deaths result each year from drug-resistant strains of common bacteria ...

'Cheater Mitochondria' May Profit from Cellular Stress Coping Mechanisms

Cheating mitochondria may take advantage of cellular mechanisms for coping with food scarcity in a simple worm to persist, even though this can reduce the worm's ...

New Drug Candidate Found for Hand, Foot and Mouth Disease

Researchers have identified a potential drug candidate against enterovirus 71, a common cause of hand, foot and mouth disease in infants and young children. The compound of interest is a small ...
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Earlier Headlines
 

A New Strategy of Cell Entry for Some Types of Parvoviruses

Researchers have uncovered a new parvovirus strategy for reaching the cell nucleus which is their site of replication. This new method of entry is a good example of host-driven ...

Mechanism That Causes Cell Nuclei to Grow

Researchers discover a mechanism that causes cell nuclei to ...

Technique Permits Convenient, Precise Optical Imaging of Individual Proteins

In a new study, researchers describe a method for examining proteins in keen detail. To do this, his group makes clever use of a phenomenon known as surface plasmon resonance (SPR), incorporating it ...

A Scientific First: How Psychedelics Bind to Key Brain Cell Receptor

For the first time, scientists solved the high-resolution structure of these compounds when they are actively bound to the 5-HT2A serotonin receptor on the surface of brain cells. This discovery is ...

'Cellular Compass' Guides Stem Cell Division in Plants

Biologists observing the formation of leaves noticed the nuclei moved in bewildering ways. Further investigation uncovered proteins that act as compasses and motors, guiding the divisions of ...

Engineered Bacteria Churn out Cancer Biomarkers

Pity the glycan. A lab has created these very tools by commandeering simple, single-celled microorganisms - namely E. coli bacteria - and engineering them to explore the complex process of ...

Scientists Uncover the Structural Mechanism of Coronavirus Receptor Binding

The spike protein on the surface of the SARS-CoV-2 coronavirus can adopt at least ten distinct structural states, when in contact with the human virus receptor ACE2, according to new ...

Discovery of Microbes With Mixed Membranes Sheds New Light on Early Evolution of Life

Current research suggests that more complex life-forms, including humans, evolved from a symbiosis event between bacteria and another single-celled organism known as archaea. However, evidence of a ...

New Path to Neuron Regeneration After Spinal Cord Injury

The astrocytic glial cell has the unique ability to form scar tissue around damaged neurons. The presence of scar tissue is associated with inhibitory effects on the regrowth of mature neurons that ...

Replicating a Genome Starts With a Twist, a Pinch, and a Bit of a Dance

DNA replication begins with a set of proteins -- the Origin of Replication Complex (ORC). Researchers published images of the human ORC in exquisite detail, showing how it changes shapes in dramatic ...

Key Role of Immune Cells in Brain Infection

Researchers have identified the specific type of immune cell that induces brain inflammation in herpes simplex virus (HSV) encephalitis. Crucially, they have also determined the signalling protein ...

Tiny Protein Motor Fuels Bacterial Movement

The ability to move is key for bacteria like some strains of salmonella and E. coli to efficiently spread infections. They can propel themselves forward using threads, known as flagella, powered by ...

The Wnt Pathway Gets Even More Complicated

A new role for Casein Kinase-1 on RNF43 is ...

Two Amino Acids Are the Marie Kondo of Molecular Liquid Phase Separation

Biologists have identified unique roles for the amino acids arginine and lysine in contributing to molecule liquid phase properties and their ...

Successful Improvement of the Catalytic Activity of Photosynthetic CO2 Fixing Enzyme Rubisco

A research group have succeeded in greatly increasing the catalytic activity of Rubisco, the enzyme which fixes carbon from carbon dioxide in plant photosynthesis. The research team also hypothesized ...

Bioactive Nano-Capsules to Hijack Cell Behavior

Many diseases are caused by defects in signaling pathways of body cells. In the future, bioactive nanocapsules could become a valuable tool for medicine to control these pathways. Researchers have ...

When Methane-Eating Microbes Eat Ammonia Instead

As a side effect of their metabolism, microorganisms living on methane can also convert ammonia. In the process, they produce nitric oxide (NO), a central molecule in the global nitrogen cycle. ...

New Method to Produce Gold Nanoparticles in Cancer Cells

Researchers have developed a method of biosynthesizing plasmonic gold nanoparticles within cancer cells, without the need for conventional bench-top lab methods. It has the potential to notably ...

Gene That Drives Ovarian Cancer Identified

Scientists have pinpointed which specific genes drive - or delay - high-grade serious ovarian ...

Mutant Tomato Helps to Crack the Secrets of Fruiting

Researchers have found that fruit development in tomatoes rewires their central metabolism. The plant hormone gibberellin, which regulates major parts of plant development, triggers the process of ...

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