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Mad Cow Disease News
September 24, 2020

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First All-Human Mouse Model of Inherited Prion Disease

Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study reports a significant advance in the development of mouse models of human ...

Experimental Treatment Slows Prion Disease, Extends Life of Mice

Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' ...

Scientists Develop 'Mini-Brain' Model of Human Prion Disease

Scientists have used human skin cells to create what they believe is the first cerebral organoid system, or 'mini-brain,' for studying sporadic Creutzfeldt-Jakob disease (CJD). CJD is a ...

Soil Compound Fights Chronic Wasting Disease

A major compound in soil organic matter degrades chronic wasting disease prions and decreases infectivity in mice, according to a new ...

New Assay Reveals Biophysical Properties That Allow Certain Proteins to Infect Others

Scientists have identified a physical basis for the spread of corrupted proteins known as prions inside ...

First Artificial Human Prion Created

Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a ...

Microglia Are Key Defenders Against Prion Diseases

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists ...

Amyloid Protein Transmission Through Neurosurgery

Amyloid beta pathology -- protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new study. Researchers studied the medical records of four ...

New Brain Disease Test for Parkinson's, Dementia With Lewy Bodies

Scientists have modified a test for early diagnosis of prion diseases with the goal of improving early diagnosis of Parkinson's disease and dementia with Lewy bodies. The group tested cerebral ...

The Bright Side of an Infectious Protein

Prions are self-propagating protein aggregates that can be transmitted between cells. The aggregates are associated with human diseases. Indeed, pathological prions cause mad cow disease and in ...

Protein Associated With ALS Points to Possible Targets for Therapeutic Intervention

Scientists may have found possible targets for therapeutic interventions in the fight against Lou Gehrig's disease. A research team conducted the first single-molecule study of folding in the ...

Brain Cell Advance Brings Fresh Hope for Creutzfeldt-Jakob Disease Therapies

Scientists have developed a new system to study Creutzfeldt-Jakob disease in the laboratory, paving the way for research to find treatments for the fatal brain ...

Researchers Probe Brain Disease-Causing Proteins at the Atomic Level

Researchers studying a protein that causes a hereditary degenerative brain disease in humans have discovered that the human, mouse and hamster forms of the protein, which have nearly identical amino ...

Health: New Protein Aggregation Measurement Tool

A team of scientists have described the synthetic genetic tool they built to quantitatively sense, measure and manipulate protein aggregation in live cells. This may open the door to greater ...

Chronic Wasting Disease

New research summarizes the efforts in disease surveillance and risk management of chronic wasting disease (CWD) in deer and shows that past management strategies such as selective culling, herd ...