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Cocaine News
September 24, 2020

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A Complex Gene Program Initiates Brain Changes in Response to Cocaine

Researchers used single-nucleus RNA sequencing to compare transcriptional responses to acute cocaine in 16 unique cell populations from the brain nucleus accumbens. The atlas is part of a major study ...

Motherhood Overrides the Brain's Decision-Making

Motherhood takes over the brain's decision-making regions to prioritize caring for offspring, according to new ...

Some People Are Easily Addicted to Drugs, but Others Are Not

Researchers have discovered that dopamine D2 receptors (DRD2s) in cholinergic interneurons (ChINs) play a crucial role in cocaine ...

Novel Role for Dopamine That Impacts Gene Expression Related to Cocaine Abuse

Scientists have discovered a new role for the brain chemical dopamine that is independent of classic neurotransmission. The new role appears to be critical to changes in gene expression related to ...

Of All Professions, Construction Workers Most Likely to Use Opioids and Cocaine

Construction workers are more likely to use drugs than workers in other professions, finds a new ...

Drug Overdose Deaths in CT Doubled in 6 Years

Opioid overdose deaths in Connecticut doubled in the past 6 years, largely driven by use of multiple drugs together, according to a team of ...

Chronic Cocaine Use Modifies Gene Expression

Chronic cocaine use changes gene expression in the hippocampus, according to new research in ...

Blocking Dopamine Weakens Effects of Cocaine

Blocking dopamine receptors in different regions of the amygdala reduces drug seeking and taking behavior with varying ...

Cell-Type Specific Mechanism for Formation and Retrieval of Cocaine-Associated Memories

Scientists have revealed neuronal mechanisms underlying the formation and retrieval of cocaine use-associated memories. Their research sheds light on how drug addiction develops and reveals pathways ...

Performance-Enhancing Drugs May Increase Risk of Teen Cocaine Abuse, Impair Fertility

Performance-enhancing steroid use could increase the risk of cocaine use and addiction in teens, according to a new rodent study. The combination of these drugs could also impair fertility in young ...

Brain Research Reveals a Circuit for Cocaine Relapse

Researchers have identified which neurons are responsible for cocaine-seeking behaviors in rodents and where these neurons exert their effects within the brain. Their work opens a new line of ...

Menstrual Cycle Phase Influences Cocaine Craving

Menstrual cycle may influence addiction risk in women, according to a new ...

Why Environmental Cues Make Drug Addiction Extra Hard to Beat

Besides triggering the brain's emotional and stimulus-response systems, environmental cues activate areas where memories are processed, according to this study. Prompting these memory processing ...

Women's Hormones Play Role in Drug Addiction, Higher Relapse Rates

Female-specific interventions are needed, but in the meantime, treatment centers could use this study to educate women about their stronger mental connections to places and ...

Erasing Memories Associated With Cocaine Use Reduces Drug Seeking Behavior

Researchers identified the brain circuits that form memories associating environmental cues with cocaine use. Targeting these memories may improve the success of exposure therapy to prevent ...

Born to Run: Just Not on Cocaine

A study finds a surprising response to cocaine in a novel strain of mutant mice -- they failed to show hyperactivity seen in normal mice when given cocaine and didn't run around. In other tests, ...

Disconnect Between Brain's Dopamine System and Cocaine Addiction

Researchers have revealed significant insight into cocaine addiction, a phenomenon which has grown significantly in the United States since ...

How Exercise Could Help Fight Drug Addiction

The siren call of addictive drugs can be hard to resist, and returning to the environment where drugs were previously taken can make resistance that much harder. However, addicts who exercise appear ...

Moving the Motivation Meter

Rats given the drug that reduced dopamine were much less likely to work for preferred morsels of food. But when these rats were then given one of the experimental drugs, they regained their ...

Cluster of Cocaine-Fentanyl Overdoses in Philadelphia Underscores Need for More 'Test Strips' and Rapid Response

Emergency department physicians are calling for more readily available testing strips to identify the presence of fentanyl in patients experiencing a drug overdose, and a rapid, coordinated response ...

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