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Pharmaceuticals News
July 12, 2020

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Top Headlines
 

New research identifies several existing compounds that block replication of the COVID-19 virus (SARS-CoV-2) within human cells grown in the laboratory. The inhibitors all ...

Existing Drugs Can Prevent SARS-CoV-2 from Hijacking Cells

Researchers evaluate how the new coronavirus rewires human proteins for its own replication, and identify several antiviral drugs ready for clinical ...

Breakthrough Discovery to Transform Prostate Cancer Treatment

A novel formulation of the prostate cancer drug abiraterone acetate - currently marketed as Zytiga - will dramatically improve the quality of life for people suffering from prostate cancer, as ...

How Cancer Drugs Find Their Targets Could Lead to a New Toolset for Drug Development

Cellular processes such as transcription often take place in tiny cellular droplets called condensates. A new study shows the mechanism by which ...
Latest Headlines
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Earlier Headlines
 

Nanoparticle for Overcoming Leukemia Treatment Resistance

One of the largest problems with cancer treatment is the development of resistance to anticancer therapies. A research team found that repurposing a commonly used chemotherapy drug using a ...

Open-Source Machine Learning Tool Connects Drug Targets With Adverse Reactions

Scientists develop AI-based tool to predict adverse drug events. Such events are responsible for some 2 million U.S. hospitalizations per year. The free, open-source system could enable safer drug ...

New Nanoparticle Drug Combination for Atherosclerosis

Physicochemical cargo-switching nanoparticles (CSNP) can help significantly reduce cholesterol and macrophage foam cells in arteries, which are the two main triggers for atherosclerotic plaque and ...

Cancer: Drug With New Approach on Impeding DNA Repair Shows Promise in First Clinical Trial

Berzosertib, an ATR-targeting drug, improves progression-free survival in combination with chemotherapy in patients with high-grade serous ovarian ...

Improved Gut Microbiota With Cholesterol-Lowering Medication

There is a clear link between improved gut microbiota and one of our most common cholesterol-lowering drug groups: ...

Chemotherapy/immunotherapy Combo Shows Promise for First-Line Treatment of Mesothelioma

Inoperable malignant pleural mesothelioma, is a rare and aggressive cancer of the protective lining of the lungs, or pleura, often caused by exposure to ...

Promising Path Found for COVID-19 Therapeutics

Researchers have successfully demonstrated that a set of drug-like small molecules can block the activity of a key SARS-CoV-2 protein -- providing a promising path for new COVID-19 ...

Compound in the Gills of Clams May Fight Common Infections

A compound discovered in the gills of wood-eating clams could be the solution to a group of parasites responsible for some of the world's most common ...

Can Gut Microbiome Alter Drug Safety and Efficacy?

Researchers have developed an approach for studying how the gut microbiome chemically alters oral medications, unlocking possibilities for improving efficacy, reducing side effects, and creating ...

Potential Treatment for Rett Syndrome

An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after ...

Antibiotic Used to Treat Tuberculosis Could Be Surprise Treatment for Deadly Superbug

Through a new screening method, researchers have found that the antibiotic rifabutin is effective against life-threatening Acinetobacter ...

Scientists have recently identified a small mitochondrial uncoupler, named BAM15, that decreases the body fat mass of mice without affecting food intake and muscle mass or increasing body ...

New Killing Mechanism Discovered in 'Game-Changing' Antibiotic

Scientists have taken another step forward on their quest to develop a viable drug based on teixobactin -- a new class of potent natural antibiotic capable of killing superbugs. New research provides ...

Diet, Gut Microbes Affect Cancer Treatment Outcomes

What we eat can affect the outcome of chemotherapy - and likely many other medical treatments - because of ripple effects that begin in our gut, new research ...

A Potential New Weapon in the War Against Superbugs

Researchers have shown that a newly discovered natural antibiotic, teixobactin, could be effective in treating bacterial lung conditions such as tuberculosis and those commonly associated with ...

Cancer Treatment: New Form of Highly Targeted Drug Therapy

Scientists describe a new technology to rapidly create a homogeneous type of ADC, which attaches to a specific site on the cancer cell, with improved efficiency and potentially enhanced stability, ...

Researchers Urge Halt in Prescribing Hydroxycholoroquine for COVID-19

Researchers urge a moratorium on prescribing chloroquine or hydroxychloroquine, with or without azithromycin, to treat or prevent COVID-19, and caution that the reassuring safety profile of ...

'Excretion of Sugar Into Stool'? New Action of Anti-Diabetic Drug Discovered

A research team has discovered that metformin, the most widely prescribed anti-diabetic drug, causes sugar to be excreted in the stool. Taking advantage of the new bio-imaging apparatus PET-MRI, they ...

New Pill Could Prevent Anaphylaxis in People With Food, Drug Allergies

For someone with a food or drug allergy, the risk of life-threatening anaphylactic shock lurks around every corner. A new study shows there might be a pill that can be taken proactively to prevent ...

How Ketamine Combats Depression

The anaesthetic drug ketamine has been shown, in low doses, to have a rapid effect on difficult-to-treat depression. Researchers now report that they have identified a key target for the drug: ...

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