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Immune System News
August 13, 2020

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Top Headlines
 

Gut Microbes Shape Our Antibodies Before We Are Infected by Pathogens

Because the microbiota is so complex, containing hundreds of different bacterial species, it is not known how the presence of microbes in the intestine shaped the antibodies that are present even ...

Antibiotics Use Early in Life Increases Risk of Inflammatory Bowel Disease Later in Life

Even short, single antibiotic courses given to young animals can predispose them to inflammatory bowel disease (IBD) when they are older, according ...

Researchers Map Mechanisms in the Largest CRISPR System

The largest and most complex CRISPR system has been visualized by researchers in a new study. The system may have potential applications in biomedicine and biotechnology, the researchers ...

COVID-19 Research: Anti-Viral Strategy With Double Effect

When the SARS-CoV-2 virus penetrates human cells, it lets the human host cell produce proteins for it. One of these viral proteins, called PLpro, is essential for the replication and rapid spread of ...
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Single-Cell Analysis Provides New Insights Into Mitochondrial Diseases

Investigators have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases -- inherited disorders that interfere with energy production in the body and ...

Virus Uses Decoy Strategy to Evade Immune System

Researchers have learnt more about how viruses operate and can evade the immune system and are now using their discovery to help learn more about ...

Internal Differences: A New Method for Seeing Into Cells

The new technology may help answer outstanding questions about the immune system, cancer, Alzheimer's, and ...

Move Over Akita: Introducing 'Kuma Mutant' Mice for Islet Transplantation Research

Scientists have used a gene editing technique to establish a novel mouse model of permanent neonatal diabetes -- the immune-deficient Kuma mutant mice with a specific deletion in the Insulin2 (Ins2) ...

COVID-19 Should Be Treated as an Acute Inflammatory Disease, Scientist Suggests

A team of scientists conducted a comprehensive analysis of worldwide COVID-19 data to identify key strategies moving forward to develop effective therapeutics. The scientists suggest that COVID-19 ...

How Tumor Cells Evade the Immune Defense

Scientists are increasingly trying to use the body's own immune system to fight cancer. A new study now shows the strategies tumor cells use to evade this attack. The method developed for this ...

Tool Could Improve Success in Translating Drugs from Animal Studies to Humans

A new computational tool could help better determine which drugs should move from animal testing to humans. It could also sooner detect a reason why a drug might fail, guiding how a clinical trial ...

Identification of a New Mechanism in the Immune System Provides Knowledge About Diseases

A recently identified mechanism in the immune system reveals a previously unknown protein that could provide an opening to a better understanding of infections and autoimmune ...

The Wrong Track: How Papillomaviruses Trick the Immune System

Specific antibodies protect us against viral infections - or do they not? Researchers studied the immune response to papillomaviruses in mice and discovered a hitherto unknown mechanism by which the ...

Assembly Within the Tumor Center

Number of macrophages in tumor tissue enables prognosis of lung tumor ...

Exposure to Common Cold Coronaviruses Can Teach the Immune System to Recognize SARS-CoV-2

A new study shows that memory helper T cells that recognize common cold coronaviruses also recognize matching sites on SARS-CoV-2, the virus that causes ...

MIS-C Different from Severe COVID-19 in Children

Researchers report important data that differentiate MIS-C from severe COVID-19 in children and suggest that MIS-C is a post-infectious syndrome related to COVID-19 but distinct from Kawasaki ...

The Enemy Within: Safeguarding Against the Spread of Intracellular Bacteria

Researchers have revealed the multiple, intertwined cell death systems that prevent the spread of the 'intracellular' bacterium Salmonella, an important cause of typhoid fever which kills ...

Could Prior Exposure to Common Cold Viruses Affect the Severity of SARS-CoV-2 Symptoms?

A new study shows that some healthy individuals possess immune cells capable of recognizing the novel coronavirus, SARS-CoV-2. The reason for this might be found in prior infections with 'common ...

Gene Variations at Birth Reveal Origins of Inflammation and Immune Disease

A study has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, ...

Immunoprotein Impairs SARS-CoV-2

A protein produced by the human immune system can strongly inhibit corona viruses, including SARS-CoV-2, the pathogen causing Covid-19. Researchers successfully showed that the LY6E-Protein prevents ...

The Big Gulp: Inside-out Protection of Parasitic Worms Against Host Defenses

A team of developmental biologists at the Morgridge Institute for Research has discovered a means by which schistosomes, parasitic worms that infect more than 200 million people in tropical climates, ...

Immune System Variation Can Predict Severe COVID-19 Outcomes

The differing immune system responses of patients with COVID-19 can help predict who will experience moderate and severe consequences of disease, according to a new ...

Protecting Beta Cells Against Stress May Guard Against Type 1 Diabetes

Researchers have found an unusual strategy that eventually may help to guard transplanted beta cells or to slow the original onset of type 1 ...

Tracking Antibody Profiles for Influenza Exposures Across the Lifespan

Immune responses to influenza exposures increase early in life, then decline in middle age, according to a new ...

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